Kyoto Univ: Transplanting iPS cartilage tissue into patients: Regeneration of articular cartilage damage
Kyoto University Hospital:
Cartilage tissue prepared from other people’s iPS cells,
For patients with injured knee cartilage
Clinical research to transplant.
Transplanting iPS cartilage tissue into a patient:
On April 23, it was revealed that it had been transplanted to patients.
The timing and number of transplants and the gender and age of the patients were not disclosed.
For 4 patients:
Four patients aged 20 to 70 have severe knee cartilage damage due to traffic accidents and sports.
Using iPS cells stockpiled by Kyoto University, cartilage tissue with a diameter of several millimeters is created and transplanted to the affected area.
Ministry of Health, Labor and Welfare approves plan:
It takes one year after surgery to integrate with the cartilage remaining around it.
See if you can relieve the pain.
In January last year, a subcommittee of the Ministry of Health, Labor and Welfare approved the plan.
Challenges with traditional therapies:
Conventionally, there is a treatment method in which a part is collected from a part other than the affected area and transplanted.
However, it is difficult to collect a sufficient amount by the conventional treatment method.
In addition, there is a problem that even if it is transplanted, it may not work normally.
(Sankei Shimbun)
http://topics.smt.docomo.ne.jp/article/sankei/life/sankei-lif2104230046
Regeneration of articular cartilage damage by iPS cell-derived cartilage transplantation
CiRA | Center for iPS Cell Research and Application, Kyoto University
Knee osteoarthritis
Knee osteoarthritis can cause discomfort and pain when moving or walking the knee.
Transplanting normal cartilage into the damaged area is the preferred treatment.
Preparation of iPS cell-derived cartilage:
We have accumulated research to produce high quality cartilage from human iPS cells.
And we succeeded in producing iPS cell-derived cartilage.
The results of this research have made it possible to supply a sufficient amount of high-quality cartilage to the damaged part of the knee osteoarthritis cartilage injury.
https://www.cira.kyoto-u.ac.jp/j/pressrelease/news/200124-193000.html