Tokyo Univ: Super flexible nano mesh sensor – Measurement of "human iPS cardiomyocyte sheet" –

Tokyo Univ: Super flexible nano mesh sensor – Measurement of “human iPS cardiomyocyte sheet” –

~ Quantitatively evaluate the side effects of new drugs on the heart, expectation for application to drug discovery field ~

The University of Tokyo Faculty of Engineering, RIKEN – Center for Emergent Properties and Science:

Together with Tokyo Women’s Medical University Advanced Biomedical Research Institute,

We developed a sensor using electrodes as nanometer as soft as the cells.

With the beating continued, the distribution of the surface potential is stably measured over 96 hours.

Nanomesh sensor:

This sensor maintains high liquid permeability.

This sansar is brought into direct contact with myocardium sheet and medication is administered.

Then you can quantitatively measure changes in surface potential (before and after dosing).

In the future, it will be applied to myocardial sheet drug discovery and regenerative medicine.

The results of this research were published online on December 31, 2018 (UK time) in the UK scientific journal “Nature Nanotechnology”.