COVID-19: France’s Alsachim SAS releases 6 types of analytical reagents: Measuring drug concentration in blood
COVID-19:
Shimadzu:
French subsidiary / Alsachim SAS will release stable isotope reagents from May 11th.
This reagent corresponds to “6 new drugs that are new coronaviruses / therapeutic drug candidates”.
Development / Manufacturer: Group company France Alsachim SAS (ALC)
Domestic sales: Shimadzu GLC is in charge,
Stable isotope reagent:
A reagent that is “atom / stable isotope labeled with similar chemical properties but different mass numbers”.
It is often used as an internal standard substance when performing quantitative analysis using a mass spectrometer.
Blood drug monitoring: (TDM)
In Western hospitals, blood drug monitoring (TDM) using liquid chromatograph mass spectrometer (LC-MS) is popular.
When administering an immunosuppressive drug to a patient, “TDM, which measures and monitors the drug concentration in blood, is an effective means for precisely controlling the dosage.”
Blood drug levels: therapeutic effects and side effects
In drug development by pharmaceutical companies and research institutes, the relationship between therapeutic effects and side effects and drug concentration in blood is investigated.
At this time, stable isotope reagents are used for quantitative analysis by LC-MS.
Currently, pharmaceutical companies all over the world are aiming to shorten the development period by converting already developed drugs.
France Alsachim SAS (ALC):
In March of this year, we developed stable isotope reagents such as lemdecivir and favipiravir for measuring drug concentration.
Currently, it is mainly sold in Europe.
Shimadzu: ALC
We will continue to support pharmaceutical company drug development (CRO) and new coronavirus therapeutic drug development at medical institutions.
Alsachim: stable isotope reagent
Corresponding candidate drug for new coronavirus
Remdecibir: Ebola treatment
Favipiravir: new influenza drug
Nafamostat (Fusan®): Acute pancreatitis treatment agent
Lopinavir, ritonavir (Kaletra®): HIV treatment
Hydroxychloroquine (Pracenil®): Antimalarial agent
Chloroquine: antimalarial
2020 | News | Shimadzu