COVID-19: Measure mutant strains and antibody levels in 8 minutes!
-Take a drop of blood from your fingertip-
RIKEN:
Take a drop of blood from a fingertip from a patient with the new coronavirus.
Corresponding to multiple mutant strains,
The amount of antibody can be automatically measured in 8 minutes with the same accuracy as a detailed test.
Fields of system use:
Precise and rapid measurement of antibody levels in individual blood at medical sites.
It is used to determine whether the person needs to be given a booster vaccination.
(Nippon Television News) – Yahoo! News
https://news.yahoo.co.jp/articles/e9374a123a45ff8e58a21f14942dd5e5a10b8f69
Automatic quantification of antibody amount of new coronavirus mutant strain in 8 minutes | RIKEN
https://www.riken.jp/press/2022/20220802_2/index.html
COVID-19 : Mesurez les souches mutantes et les niveaux d’anticorps en 8 minutes !
-Prenez une goutte de sang du bout de votre doigt-
RIKEN :
Prélevez une goutte de sang du bout du doigt d’un patient atteint du nouveau coronavirus.
Correspondant à plusieurs souches mutantes,
La quantité d’anticorps peut être automatiquement mesurée en 8 minutes avec la même précision qu’un test détaillé.
Domaines d’utilisation du système :
Mesure précise et rapide des niveaux d’anticorps dans le sang individuel sur les sites médicaux.
Il est utilisé pour déterminer si la personne doit recevoir une vaccination de rappel.
(Nippon Television News) – Yahoo! Actualités
Quantification automatique de la quantité d’anticorps de la nouvelle souche mutante de coronavirus en 8 minutes | RIKEN
COVID-19: Messen Sie Mutantenstämme und Antikörperspiegel in 8 Minuten!
-Nehmen Sie einen Tropfen Blut aus Ihrer Fingerbeere-
RIKEN:
Nehmen Sie einem Patienten mit dem neuen Coronavirus einen Tropfen Blut aus der Fingerbeere.
Entsprechend mehreren Mutantenstämmen,
Die Antikörpermenge kann automatisch in 8 Minuten mit der gleichen Genauigkeit wie ein detaillierter Test gemessen werden.
Einsatzbereiche des Systems:
Präzise und schnelle Messung des Antikörperspiegels im individuellen Blut an medizinischen Einrichtungen.
Es wird verwendet, um festzustellen, ob die Person eine Auffrischungsimpfung erhalten muss.
(Nippon Television News) – Yahoo!-Nachrichten
Automatische Quantifizierung der Antikörpermenge des neuen Coronavirus-Mutantenstamms in 8 Minuten | RIKEN
Rapid and quantitative detection of multiple antibodies against SARS-CoV-2 mutant proteins by photo-immobilized microarray
SpringerLink
Abstract
A rapid automatic quantitative diagnostic system for multiple SARS-CoV-2 mutant protein-specific antibodies
was developed using a microarray with photoreactive polymers.
Two types of photoreactive polymers, phenylazide and polyoxyethylene, were prepared.
The polymers were coated on a plastic plate.
Aqueous solutions of mutant virus proteins were microspotted on the coated plate and immobilized by photoirradiation.
Virus-specific IgG in the serum or blood
was automatically assayed using an instrument that we developed for pipetting, reagent stirring, and washing.
The results highly correlated with those of the conventional enzyme-linked immunoassay or immunochromatography.
This system was successfully used to test the sera or blood from the patients recovered from the infection and the vaccinated individuals.
The recovered individuals had antibodies against the nucleoprotein, in contrast to the vaccinated individuals.
The amount of antibodies produced decreased with an increase in virus mutation.
Blood collected from the fingertip (5 μL) and a test period of 8 min were sufficient conditions for conducting multiple antibody assays.
We believe that our system would facilitate rapid and quantitative automatic assays and aid in the diagnosis of various viral infectious diseases and assessment of the immune status for clinical applications.
https://link.springer.com/article/10.1007/s44211-022-00161-z