约翰·霍普金斯大学(Johns Hopkins)对感染COVID-19的住院患者进行依维菌素研究
对普通和经济型抗寄生虫药伊维菌素(思美达克)的研究兴趣
由于享有盛名的约翰斯·霍普金斯大学的西德尼·金梅尔综合癌症中心计划于6月启动一项临床试验,该计划将继续发展。
在SARS-CoV-2住院患者中,COVID-19大流行背后的病毒
位于马里兰州巴尔的摩的调查员
将比卡鲁胺或伊维菌素的治疗标准进行比较。
他们正在加入越来越多的研究中心,以寻求有效和安全的治疗方法。
该小组采取的方法与肯塔基大学的研究方法截然不同,后者的研究重点是在家中患有COVID-19较轻病例的患者。
Context
A growing number of research centers around the world are investigating the use of Ivermectin as a potential therapy targeting SARS-CoV-2.
The idea started thanks to a group of creative and out-of-the-box thinking scientists in Australia.
The word spread and now a number of companies, academic medical centers, and governments are exploring the use of the anti-parasitic drug as a possible therapy.
The upside could be huge:
the drug is inexpensive and available.
In fact, Merck even helps developing nations by giving the drug, called Stromectol, away in some cases.
Now Johns Hopkins investigates ivermectin and an anti-androgen drug known as Bicalutamide—used together or with another hormone to treat prostate cancer.
The Study
Planned to commence June 2020 for a year, theSidney Kimmel Comprehensive Cancer Center at Johns Hopkins
will probe into whether bicalutamide or ivermectin can have an impact on hospitalized patients infected with SARS-CoV-2.
Led by Principal Investigator Catherine H. Marshall, MD, MPH, and a team of sub-investigators listed below,
the team will study two groups including one randomized group receiving Bicalutamide Casodex) 150 mg by mouth daily for seven (7) days versus plus the standard of care for COVID-19
versus
the use of versus a study group receiving Ivermectin (Stromectol/Soolantra/Sklice) 600 µg/kg (maximum dose of 60mg) by mouth daily for three days with the possibility of extension to six (6) days if still hospitalized and approved by the Data and Safety Monitoring Board.
伊维菌素:大村聪:抗寄生虫药的潜力
大村中敏/诺贝尔奖得主说:
伊维菌素是一种40年前开发的抗寄生虫药,可能对新的冠状病毒感染有效。
从今年四月开始,这样的消息就来了。
伊维菌素:
伊维菌素是一种寄生虫控制药物。
自2012年以来,
例如艾滋病毒和登革热,
通常,针对称为黄病毒的病毒,
在体外有效(体外测试),
我已经知道了
黄病毒类型:
新的冠状病毒也是黄病毒的一种。
从澳大利亚的研究报告开始,
美国,
英国,
法国,
西班牙,
泰国,
波多黎各,
玻利维亚,
秘鲁……
临床试验已经在世界各地的大学和医院开始。
约翰霍普金斯大学是传染病研究的圣地,它宣布将开始临床研究,并且人们的期望值正在上升。
― Bungeishunju特集(Bunshun在线)
https://news.yahoo.co.jp/articles/f2c014a21714b637017e52cd66b39da7783b2b1c