COVID-19：证明病毒具有灭活作用：Care222TM UV
〜有望用于感染控制〜
重新测试结果：
在世界上，我们首次揭示了新的冠状病毒在222 nm的中心波长下的灭活作用。
222nm紫外线比254nm紫外线对人眼和皮肤更安全。有望将其应用于新的冠状病毒传染病的感染控制。
广岛大学医院：USHIO INC。
广岛大学医院病毒学专家坂口武正教授的团队是Care222TM USHIO INC。
用来澄清世界上第一次灭活新的冠状病毒的效果。
Care222TM：
由USHIO INC。制造的紫外线灯。
KrCl准分子灯输出的紫外线
窄波长带滤光片
紫外灯在200-230 nm区域，峰值为222 nm。
灭活效果：
在干燥的塑料环境中，
222 nm紫外线，照度为0.1 mW / cm2，
通过照射30秒，
确认有99.7％的新冠状病毒失活。
这项研究的结果发表在《美国感染控制杂志》的在线版本上。
广岛大学
https://www.hiroshima-u.ac.jp/news/59996
Effectiveness of 222-nm ultraviolet light on disinfecting SARS-CoV-2 surface contamination – American Journal of Infection Control
Highlights
•222-nm UVC light (0.1 mW/cm2) reduced viable SARS-CoV-2 by 0.94 log10 in 10 s•222-nm UVC light (0.1 mW/cm2) reduced viable SARS-CoV-2 by 2.51 log10 in 30 s•222-nm UVC light did not reduce SARS-CoV-2 RNA copy number after 5 min irradiation•TSID50 and not RT-qPCR should be used to monitor far-UVC disinfection of surfaces
Abstract
Background
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), has emerged as a serious threat to human health worldwide. Efficient disinfection of surfaces contaminated with SARS-CoV-2 may help prevent its spread. This study aimed to investigate the in vitroefficacy of 222-nm far-ultraviolet light (UVC) on the disinfection of SARS-CoV-2 surface contamination.
Methods
We investigated the number of viable SARS-CoV-2 after UV irradiation (0.1 mW/cm2) at 222 nm for 10–300 s using the 50% tissue culture infectious dose (TCID50). In addition, we used quantitative reverse transcription polymerase chain reaction to quantify SARS-CoV-2 RNA under the same conditions.
Results
One and 3 mJ/cm2 of 222 nm UVC irradiation (0.1 mW/cm2 for 10 and 30 s) resulted in 88.5 and 99.7% reduction of viable SARS-CoV-2 based on the TCID50 assay, respectively. In contrast, the copy number of SARS-CoV-2 RNA did not change after UVC irradiation even after a 5-min irradiation.
Conclusion
This study shows the efficacy of 222-nm UVC irradiation against SARS-CoV-2 contamination in an in vitro experiment. Further evaluation of the safety and efficacy of 222-nm UVC irradiation in reducing the contamination of real-world surfaces and the potential transmission of SARS-CoV-2 is needed.
https://www.ajicjournal.org/article/S0196-6553(20)30809-9/fulltext